ProfileOfResearchers

TITLE: A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic
AUTHORS: Lerias, JR; Pinto, MC; Botelho, HM ; Awatade, NT; Quaresma, MC; Silva, IAL; Wanitchakool, P; Schreiber, R; Pepperkok, R; Kunzelmann, K; Amaral, MD ;
PUBLISHED: 2018, SOURCE: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, VOLUME: 1865, ISSUE: 2

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TITLE: Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1
AUTHORS: Lerias, J; Pinto, M; Benedetto, R; Schreiber, R; Amaral, M ; Aureli, M; Kunzelmann, K;
PUBLISHED: 2018, SOURCE: CELLULAR SIGNALLING, VOLUME: 44

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TITLE: Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1
AUTHORS: Lérias, J; Pinto, M; Benedetto, R; Schreiber, R; Amaral, M ; Aureli, M; Kunzelmann, K;
PUBLISHED: 2018, SOURCE: Cellular Signalling, VOLUME: 44

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TITLE: Cystic fibrosis newborn screening in Portugal: PAP value in populations with stringent rules for genetic studies
AUTHORS: Marcão, A; Barreto, C; Pereira, L; Vaz, LG; Cavaco, J; Casimiro, A; Félix, M; Silva, TR; Barbosa, T; Freitas, C; Nunes, S; Felício, V; Lopes, L; Amaral, M ; Vilarinho, L;
PUBLISHED: 2018, SOURCE: International Journal of Neonatal Screening, VOLUME: 4, ISSUE: 3

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TITLE: Cystic fibrosis: Beyond the airways. Report on the meeting of the basic science working group in Loutraki, Greece
AUTHORS: Amaral, MD ; Boj, SF; Shaw, J; Leipziger, J; Beekman, JM;
PUBLISHED: 2018, SOURCE: JOURNAL OF CYSTIC FIBROSIS, VOLUME: 17, ISSUE: 4

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TITLE: Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting small molecule
AUTHORS: Liu, J; Bihler, H; Farinha, CM; Awatade, NT; Romao, AM; Mercadante, D; Cheng, Y; Musisi, I; Jantarajit, W; Wang, YT; Cai, ZW; Amaral, MD ; Mense, M; Sheppard, DN;
PUBLISHED: 2018, SOURCE: BRITISH JOURNAL OF PHARMACOLOGY, VOLUME: 175, ISSUE: 7

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TITLE: Prolonged co-treatment with HGF sustains epithelial integrity and improves pharmacological rescue of Phe508del-CFTR
AUTHORS: Matos, AM; Gomes Duarte, A; Faria, M; Barros, P; Jordan, P ; Amaral, MD ; Matos, P ;
PUBLISHED: 2018, SOURCE: SCIENTIFIC REPORTS, VOLUME: 8, ISSUE: 1

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TITLE: Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation Full Text
AUTHORS: Canato, S; Santos, JD; Carvalho, AS; Aloria, K; Amaral, MD ; Matthiesen, R; Falcao, AO ; Farinha, CM;
PUBLISHED: 2018, SOURCE: CELLULAR AND MOLECULAR LIFE SCIENCES, VOLUME: 75, ISSUE: 24

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TITLE: Biobanking: towards increased access of biomaterials in cystic fibrosis. Report on the pre-conference meeting to the 13th ECFS Basic Science Conference, Pisa, 30 March-2 April, 2016
AUTHORS: Beekman, JM; Wang, CM; Casati, S; Tuggle, KL; Gulmans, VAM; Amaral, M ; De Boeck, K;
PUBLISHED: 2017, SOURCE: JOURNAL OF CYSTIC FIBROSIS, VOLUME: 16, ISSUE: 5

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TITLE: Epithelial Chloride Transport by CFTR Requires TMEM16A
AUTHORS: Roberta Benedetto; Jiraporn Ousingsawat; Podchanart Wanitchakool; Yong Zhang; Michael J Holtzman; Margarida Amaral ; Jason R Rock; Rainer Schreiber; Karl Kunzelmann;
PUBLISHED: 2017, SOURCE: Scientific Reports, VOLUME: 7, ISSUE: 1

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