ProfileOfResearchers

TITLE: Polyglutamine spinocerebellar ataxias: emerging therapeutic targets
AUTHORS: Neves Carvalho, A; Duarte Silva, S; Teixeira Castro, A; Maciel, P ;
PUBLISHED: 2020, SOURCE: EXPERT OPINION ON THERAPEUTIC TARGETS, VOLUME: 24, ISSUE: 11

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TITLE: Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation
AUTHORS: Mondanelli, G; Coletti, A; Greco, FA; Pallotta, MT; Orabona, C; Iacono, A; Belladonna, ML; Albini, E; Panfili, E; Fallarino, F; Gargaro, M; Manni, G; Matino, D; Carvalho, A; Cunha, C; Maciel, P ; Di Filippo, M; Gaetani, L; Bianchi, R; Vacca, C; Iamandii, IM; Proietti, E; Boscia, F; Annunziato, L; Peppelenbosch, M; Puccetti, P; Calabresi, P; Macchiarulo, A; Santambrogio, L; Volpi, C; Grohmann, U; ...More
PUBLISHED: 2020, SOURCE: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, VOLUME: 117, ISSUE: 7

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TITLE: Prevalence of Machado-Joseph disease (MJD/SCA3) explained by migration and multiple founder effects
AUTHORS: Martins, S; Costa, IPD; Giunti, P; Watanabe, M; Sasaki, H; Almeida, BC; Amorim, A; Gaspar, C; Nicholson, G; Saraiva Pereira, ML; Tsuji, S; Li, Q; Chen, S; Landoure, G; Maciel, P ; Zaltzman, R; Sharony, R; Zhou, Y; Barros, J; Loureiro, JL; Cruz, VT ; Ruano, L; Brunt, ERP; Marc M Corral Juan; Hsieh, M; Tranebjaerg, L; Olajumoke, O; Ogun, SA; Finkel, MF; Gordon, C; Cornejo Olivas, M; Fischbeck, K; Matilla Duenas, A; Volpini, V; Riess, O; Wu, Z; Rouleau, GA; Jardim, LB; Stevanin, G; Brice, A; Coutinho, P; Soong, B; Ranum, LP; Durr, A; Sequeiros, J; ...More
PUBLISHED: 2020, SOURCE: EUROPEAN JOURNAL OF HUMAN GENETICS, VOLUME: 28, ISSUE: SUPPL 1

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TITLE: Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons
AUTHORS: Seabra, CM; Aneichyk, T; Erdin, S; Tai, DJC; De Esch, CEF; Razaz, P; An, Y; Manavalan, P; Ragavendran, A; Stortchevoi, A; Abad, C; Young, JI; Maciel, P ; Talkowski, ME; Gusella, JF;
PUBLISHED: 2020, SOURCE: MOLECULAR AUTISM, VOLUME: 11, ISSUE: 1

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TITLE: Unravelling the anticancer potential of functionalized chromeno[2,3-b ] pyridines for breast cancer treatment Full Text
AUTHORS: Oliveira Pinto, S; Pontes, O; Lopes, D; Sampaio Marques, B ; Costa, MD; Carvalho, L; Goncalves, CS; Costa, BM ; Maciel, P ; Ludovico, P ; Baltazar, F; Proenca, F ; Costa, M;
PUBLISHED: 2020, SOURCE: BIOORGANIC CHEMISTRY, VOLUME: 100

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TITLE: A glucocorticoid receptor-dependent mechanism of bile acid action with therapeutic impact in polyglutamine disease Full Text
AUTHORS: Silva, JD; Duarte Silva, S; Neves Carvalho, A; Soares Cunha, C; Correia, J; Nogueira Goncalves, G; Oliveira, S; Teixeira Castro, A; Maciel, P ;
PUBLISHED: 2019, SOURCE: ISN-ASN Meeting in JOURNAL OF NEUROCHEMISTRY, VOLUME: 150

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TITLE: Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in beta amyloid-induced neurodegeneration. Full Text
AUTHORS: de Campos, ABS; Duarte Silva, S; Neves Carvalho, A; Nogueira Goncalves, G; Silva Fernandes, A; Teixeira Castro, A; Brites, D; Ambrosio, AF; Maciel, P ;
PUBLISHED: 2019, SOURCE: 14th European Meeting on Glial Cells in Health and Disease (GLIA) in GLIA, VOLUME: 67

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TITLE: Citalopram Reduces Aggregation of ATXN3 in a YAC Transgenic Mouse Model of Machado-Joseph Disease Full Text
AUTHORS: Ashraf, NS; Duarte Silva, S; Shaw, ED; Maciel, P ; Paulson, HL; Teixeira Castro, A; Costa, MD;
PUBLISHED: 2019, SOURCE: MOLECULAR NEUROBIOLOGY, VOLUME: 56, ISSUE: 5

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TITLE: From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation
AUTHORS: Da Silva, JD; Teixeira Castro, A; Maciel, P ;
PUBLISHED: 2019, SOURCE: NEUROTHERAPEUTICS, VOLUME: 16, ISSUE: 4

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TITLE: Genomic imbalances defining novel intellectual disability associated loci
AUTHORS: Lopes, F; Torres, F; Soares, G; Barbosa, M; Silva, J; Duque, F; Rocha, M; Sa, J; Oliveira, G; Sa, MJ ; Temudo, T; Sousa, S; Marques, C; Lopes, S; Gomes, C; Barros, G; Jorge, A; Rocha, F; Martins, C; Mesquita, S; Loureiro, S; Cardoso, EM; Calix, MJ; Dias, A; Martins, C; Mota, CR; Antunes, D; Dupont, J; Figueiredo, S; Figueiroa, S; Gama de Sousa, S; Cruz, S; Sampaio, A ; Eijk, P; Weiss, MM; Ylstra, B; Rendeiro, P; Tavares, P; Reis Lima, M; Pinto Basto, J; Fortuna, AM; Maciel, P ; ...More
PUBLISHED: 2019, SOURCE: ORPHANET JOURNAL OF RARE DISEASES, VOLUME: 14, ISSUE: 1

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