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TITLE: Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications
AUTHORS: Augustijns, P; Vertzoni, M; Reppas, C; Langguth, P; Lennernas, H; Abrahamsson, B; Hasler, WL; Baker, JR; Vanuytsel, T; Tack, J; Corsetti, M; Bermejo, M; Paixao, P ; Amidon, GL; Hens, B;
PUBLISHED: 2020, SOURCE: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, VOLUME: 155
INDEXED IN: Scopus WOS CrossRef: 21
22
TITLE: Physiologically-Based Pharmacokinetic Model on the Oral Drug Absorption in Roux-en-Y Gastric Bypass Bariatric Patients: Amoxicillin Tablet and Suspension
AUTHORS: Montanha, MC; Diniz, A; Silva, NMEN; Kimura, E; Paixão, P ;
PUBLISHED: 2019, SOURCE: Molecular Pharmaceutics, VOLUME: 16, ISSUE: 12
INDEXED IN: Scopus CrossRef: 5
23
TITLE: Reduced bioavailability of oral amoxicillin tablets compared to suspensions in Roux-en-Y gastric bypass bariatric subjects
AUTHORS: Montanha, MC; Magon, TFD; Alcantara, CD; Simoes, CF; Bin Silva, SR; Kuroda, CM; Yamada, SS; de Oliveira, LES; Nasser, D; Nardo, N; Mazucheli, J; Diniz, A; Paixao, PJPA ; Kimura, E;
PUBLISHED: 2019, SOURCE: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, VOLUME: 85, ISSUE: 9
INDEXED IN: Scopus WOS CrossRef: 10
24
TITLE: Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded '21st Century BA/BE' project
AUTHORS: Hens, B; Sinko, PD; Job, N; Dean, M; Al Gousous, J; Salehi, N; Ziff, RM; Tsume, Y; Bermejo, M; Paixao, P ; Brasseur, JG; Yu, A; Talattof, A; Benninghoff, G; Langguth, P; Lennernas, H; Hasler, WL; Marciani, L; Dickens, J; Shedden, K; Sun, DX; Amidon, GE; Amidon, GL; ...More
PUBLISHED: 2018, SOURCE: INTERNATIONAL JOURNAL OF PHARMACEUTICS, VOLUME: 548, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 38
25
TITLE: Functionalization of PLGA Nanoparticles with 1,3-beta-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages
AUTHORS: Tukulula, M; Gouveia, L; Paixao, P ; Hayeshi, R; Naicker, B; Dube, A;
PUBLISHED: 2018, SOURCE: PHARMACEUTICAL RESEARCH, VOLUME: 35, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef: 17
26
TITLE: Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach
AUTHORS: Paixao, P ; Bermejo, M; Hens, B; Tsume, Y; Dickens, J; Shedden, K; Salehi, N; Koenigsknecht, MJ; Baker, JR; Hasler, WL; Lionberger, R; Fan, JH; Wysocki, J; Wen, B; Lee, A; Frances, A; Amidon, GE; Yu, A; Benninghoff, G; Lobenberg, R; Talattof, A; Sun, DX; Amidon, GL; ...More
PUBLISHED: 2018, SOURCE: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, VOLUME: 129
INDEXED IN: Scopus WOS CrossRef: 25
27
TITLE: Implementing the additional strength biowaiver for generics: EMA recommended approaches and challenges for a US-FDA submission
AUTHORS: Cardot, JM; Garcia Arieta, A; Paixao, P ; Tasevska, I; Davit, B;
PUBLISHED: 2018, SOURCE: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, VOLUME: 111
INDEXED IN: Scopus WOS CrossRef: 4
28
TITLE: Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans - Part 2: Fed State
AUTHORS: Paixão, P ; Bermejo, M; Hens, B; Tsume, Y; Dickens, J; Shedden, K; Salehi, N; Koenigsknecht, MJ; Baker, JR; Hasler, WL; Lionberger, R; Fan, J; Wysocki, J; Wen, B; Lee, A; Frances, A; Amidon, GE; Yu, A; Benninghoff, G; Löbenberg, R; Talattof, A; Sun, D; Amidon, GL; ...More
PUBLISHED: 2018, SOURCE: Molecular Pharmaceutics, VOLUME: 15, ISSUE: 12
INDEXED IN: Scopus CrossRef: 11
29
TITLE: Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 1: Fasted State Conditions
AUTHORS: Bermejo, M; Paixao, P ; Hens, B; Tsume, Y; Koenigsknecht, MJ; Baker, JR; Hasler, WL; Lionberger, R; Fan, JH; Dickens, J; Shedden, K; Wen, B; Wysocki, J; Lobenberg, R; Lee, A; Frances, A; Amidon, GE; Yu, A; Salehi, N; Talattof, A; Benninghoff, G; Sun, DX; Kuminek, G; Cavanagh, KL; Rodriguez Hornedo, N; Amidon, GL; ...More
PUBLISHED: 2018, SOURCE: MOLECULAR PHARMACEUTICS, VOLUME: 15, ISSUE: 12
INDEXED IN: Scopus WOS CrossRef: 23
30
TITLE: Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model
AUTHORS: Hens, B; Talattof, A; Paixao, P ; Bermejo, M; Tsume, Y; Lobenberg, R; Amidon, GL;
PUBLISHED: 2018, SOURCE: AAPS JOURNAL, VOLUME: 20, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef: 20
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