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172

TITLE: Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors Full Text
AUTHORS: Clemente, A; Domingos, A; Grancho, AP; Iley, J; Moreira, R ; Neres, J; Palma, N; Santana, AB; Valente, E;
PUBLISHED: 2001, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 11, ISSUE: 8

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173

TITLE: Kinetics and mechanism of hydrolysis of N-amidomethylsulfonamides
AUTHORS: Iley, J; Lopes, F ; Moreira, R ;
PUBLISHED: 2001, SOURCE: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, ISSUE: 5

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174

TITLE: Acyloxymethyl as a drug protecting group. Part 6 Full Text
AUTHORS: Francisca Lopes ; Rui Moreira ; Jim Iley;
PUBLISHED: 2000, SOURCE: Bioorganic & Medicinal Chemistry, VOLUME: 8, ISSUE: 4

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175

TITLE: Acyloxymethyl as a drug protecting group. Part 6: N-acyloxymethyl- and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group Full Text
AUTHORS: Lopes, F ; Moreira, R ; Iley, J;
PUBLISHED: 2000, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY, VOLUME: 8, ISSUE: 4

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176

TITLE: Acyloxymethyl as a drug protecting group. Part 7: Tertiary sulfonamidomethyl ester prodrugs of benzylpenicillin: Chemical hydrolysis and anti-bacterial activity Full Text
AUTHORS: Iley, J; Barroso, H ; Moreira, R ; Lopes, F ; Calheiros, T;
PUBLISHED: 2000, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY, VOLUME: 8, ISSUE: 7

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177

TITLE: Acyloxymethyl as a drug protecting group. Part 5. Kinetics and mechanism of the hydrolysis of tertiary N-acyloxymethylsulfonamides
AUTHORS: Lopes, F ; Moreira, R ; Iley, J;
PUBLISHED: 1999, SOURCE: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, ISSUE: 3

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178

TITLE: Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates Full Text
AUTHORS: Iley, J; Mendes, E; Moreira, R ; Souza, S;
PUBLISHED: 1999, SOURCE: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, VOLUME: 9, ISSUE: 2

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179

TITLE: Dipeptide derivatives of primaquine as transmission-blocking antimalarials: Effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates Full Text
AUTHORS: Portela, MJ; Moreira, R ; Valente, E; Constantino, L ; Iley, J; Pinto, J ; Rosa, R; Cravo, P; do Rosario, VE;
PUBLISHED: 1999, SOURCE: PHARMACEUTICAL RESEARCH, VOLUME: 16, ISSUE: 6

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180

TITLE: Metabolism of primaquine by liver homogenate fractions
AUTHORS: Constantino, L; Paixão, P; Moreira, R ; M.J Portela; V.E Do Rosario; Iley, J;
PUBLISHED: 1999, SOURCE: Experimental and Toxicologic Pathology, VOLUME: 51, ISSUE: 4-5

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