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TITLE: Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates
AUTHORS: Carboni, F; Kitowski, A; Sorieul, C; Veggi, D; Marques, MC; Oldrini, D; Balducci, E; Brogioni, B; Del Bino, L; Corrado, A; Angiolini, F; Dello Iacono, L; Margarit, I; Romano, MR; Bernardes, GJL; Adamo, R;
PUBLISHED: 2022, SOURCE: CHEMICAL SCIENCE, VOLUME: 13, ISSUE: 8
INDEXED IN: Scopus WOS
12
TITLE: Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry  Full Text
AUTHORS: Ferhati, Xhenti; Jimenez Moreno, Ester; Hoyt, Emily A.; Salluce, Giulia; Cabeza Cabrerizo, Mar; Navo, Claudio D.; Companon, Ismael; Akkapeddi, Padma; Matos, Maria J. ; Salaverri, Noelia; Garrido, Pablo; Martinez, Alfredo; Laserna, Victor; Murray, Thomas, V; Jimenez Oses, Gonzalo; Ravn, Peter; Bernardes, Goncalo J. L.; Corzana, Francisco;
PUBLISHED: 2022, SOURCE: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOLUME: 144, ISSUE: 12
INDEXED IN: Scopus WOS CrossRef: 6
13
TITLE: Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo  Full Text
AUTHORS: Kohs, Tia C. L.; Olson, Sven R.; Pang, Jiaqing; Jordan, Kelley R.; Zheng, Tony J.; Xie, Aris; Hodovan, James; Muller, Matthew; McArthur, Carrie; Johnson, Jennifer; Sousa, Barbara B.; Wallisch, Michael; Kievit, Paul; Aslan, Joseph E.; Seixas, Joao D.; Bernardes, Goncalo J. L.; Hinds, Monica T.; Lindner, Jonathan R.; McCarty, Owen J. T.; Puy, Cristina; Shatzel, Joseph J.; ...More
PUBLISHED: 2022, SOURCE: CELLULAR AND MOLECULAR BIOENGINEERING, VOLUME: 15, ISSUE: 3
INDEXED IN: Scopus WOS
14
TITLE: Structural insights into TRPV2 activation by small molecules
AUTHORS: Pumroy, Ruth A.; Protopopova, Anna D.; Fricke, Tabea C.; Lange, Iris U.; Haug, Ferdinand M.; Nguyen, Phuong T.; Gallo, Pamela N.; Sousa, Barbara B.; Bernardes, Goncalo J. L.; Yarov Yarovoy, Vladimir; Leffler, Andreas; Moiseenkova Bell, Vera Y.;
PUBLISHED: 2022, SOURCE: NATURE COMMUNICATIONS, VOLUME: 13, ISSUE: 1
INDEXED IN: Scopus WOS
15
TITLE: Transition metal mediated bioorthogonal release
AUTHORS: Sabatino, Valerio; Unnikrishnan, V. B.; Bernardes, Goncalo J. L.;
PUBLISHED: 2022, SOURCE: CHEM CATALYSIS, VOLUME: 2, ISSUE: 1
INDEXED IN: Scopus WOS
17
TITLE: Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents  Full Text
AUTHORS: Istrate, Alena; Geeson, Michael B.; Navo, Claudio D.; Sousa, Barbara B.; Marques, Marta C.; Taylor, Ross J.; Journeaux, Toby; Oehler, Sebastian R.; Mortensen, Michael R.; Deery, Michael J.; Bond, Andrew D.; Corzana, Francisco; Jimenez Oses, Gonzalo; Bernardes, Goncalo J. L.;
PUBLISHED: 2022, SOURCE: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOLUME: 144, ISSUE: 23
INDEXED IN: Scopus WOS
18
TITLE: p-Clamp-Mediated Homo- and Heterodimerization of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation  Full Text
AUTHORS: Taylor, Ross J.; Rangel, Mauricio Aguilar; Geeson, Michael B.; Sormanni, Pietro; Vendruscolo, Michele; Bernardes, Goncalo J. L.;
PUBLISHED: 2022, SOURCE: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOLUME: 144, ISSUE: 29
INDEXED IN: Scopus WOS
19
TITLE: Chemical and Enzymatic Methods for Post-Translational Protein-Protein Conjugation  Full Text
AUTHORS: Taylor, Ross J.; Geeson, Michael B.; Journeaux, Toby; Bernardes, Goncalo J. L.;
PUBLISHED: 2022, SOURCE: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, VOLUME: 144, ISSUE: 32
INDEXED IN: Scopus WOS
20
TITLE: Selective Inhibition of Bruton?s Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors
AUTHORS: Sousa, Barbara B.; De Almeida, Catia Rebelo; Barahona, Ana F.; Lopes, Raquel; Martins Logrado, Ana; Cavaco, Marco; Neves, Vera; Carvalho, Luis A. R.; Labao Almeida, Carlos; Coelho, Ana R.; Bento, Marta Leal; Lopes, Ricardo M. R. M.; Oliveira, Bruno L.; Castanho, Miguel A. R. B.; Neumeister, Peter; Deutsch, Alexander; Vladimer, Gregory I.; Krall, Nikolaus; Joao, Cristina; Corzana, Francisco; Seixas, Joao D.; Fior, Rita; Bernardes, Goncalo J. L.; ...More
PUBLISHED: 2022, SOURCE: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, VOLUME: 5, ISSUE: 11
INDEXED IN: WOS
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