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TITLE: Ametryn and Clomazone Disrupt Mitochondrial Bioenergetics in Rat Liver: Evidence for Inhibition of Complexes I and II and ATP Synthase
AUTHORS: dos Santos Silva, Heberth Paulo; Ortiz, Camila; Miranda, Camila Araujo; Veiga Bizerra, Paulo Francisco; Palmeira, Carlos Manuel ; Mingatto, Fabio Erminio;
PUBLISHED: 2025, SOURCE: TOXICS, VOLUME: 13, ISSUE: 9

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TITLE: HepG2 spheroids cultured in alginate microcapsules as a model for exploring mitochondrial and glycolytic metabolism using the Seahorse XFe24 Analyzer Full Text
AUTHORS: Miranda, Raul Ghiraldelli; Machado, Ivo F.; Rolo, Anabela Pinto; Dorta, Daniel Junqueira; Palmeira, Carlos Manuel Marques ;
PUBLISHED: 2025, SOURCE: TOXICOLOGY MECHANISMS AND METHODS, VOLUME: 35, ISSUE: 4

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TITLE: Mitochondria under fire: toxicological mechanisms of brominated flame retardants Full Text
AUTHORS: Ghiraldelli Miranda, Raul; Machado, Ivo F.; Rolo, Anabela Pinto; Dorta, Daniel Junqueira; Palmeira, Carlos M. ;
PUBLISHED: 2025, SOURCE: TOXICOLOGY MECHANISMS AND METHODS, VOLUME: 36, ISSUE: 1

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TITLE: Sestrin2 is a central regulator of mitochondrial stress responses in disease and aging Full Text
AUTHORS: Ivo Machado; Carlos Palmeira ; Anabela Rolo;
PUBLISHED: 2025, SOURCE: Ageing Research Reviews, VOLUME: 109

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TITLE: Loss of epigenetic information as a cause of mammalian aging
AUTHORS: Jae-Hyun Yang; Motoshi Hayano; Patrick T Griffin; João A Amorim; Michael S Bonkowski; John K Apostolides; Elias L Salfati; Marco Blanchette; Elizabeth M Munding; Mital Bhakta; Yap Ching Chew; Wei Guo; Xiaojing Yang; Sun Maybury-Lewis; Xiao Tian; Jaime M Ross; Giuseppe Coppotelli; Margarita V Meer; Ryan Rogers-Hammond; Daniel L Vera; Yuancheng Ryan Lu; Jeffrey W Pippin; Michael L Creswell; Zhixun Dou; Caiyue Xu; Sarah J Mitchell; Abhirup Das; Brendan L O’Connell; Sachin Thakur; Alice E Kane; Qiao Su; Yasuaki Mohri; Emi K Nishimura; Laura Schaevitz; Neha Garg; Ana-Maria Balta; Meghan A Rego; Meredith Gregory-Ksander; Tatjana C Jakobs; Lei Zhong; Hiroko Wakimoto; Jihad El Andari; Dirk Grimm; Raul Mostoslavsky; Amy J Wagers; Kazuo Tsubota; Stephen J Bonasera; Carlos M Palmeira ; Jonathan G Seidman; Christine E Seidman; Norman S Wolf; Jill A Kreiling; John M Sedivy; George F Murphy; Richard E Green; Benjamin A Garcia; Shelley L Berger; Philipp Oberdoerffer; Stuart J Shankland; Vadim N Gladyshev; Bruce R Ksander; Andreas R Pfenning; Luis A Rajman; David A Sinclair; ...More
PUBLISHED: 2024, SOURCE: Cell, VOLUME: 187, ISSUE: 5

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TITLE: SNHG1: Redefining the Landscape of Hepatocellular Carcinoma through Long Noncoding RNAs
AUTHORS: Fonseca, Tiago S.; Martins, Rui Miguel; Rolo, Anabela P.; Palmeira, Carlos M. ;
PUBLISHED: 2024, SOURCE: BIOMEDICINES, VOLUME: 12, ISSUE: 8

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TITLE: Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer's Disease Full Text
AUTHORS: Lopes, Catia R.; Silva, Joana S.; Santos, Joana; Rodrigues, Matilde S.; Madeira, Daniela; Oliveira, Andreia; Moreira de Sa, Ana; Lourenco, Vanessa S.; Goncalves, Francisco Q.; Silva, Henrique B.; Simoes, Ana Patricia; Rolo, Anabela P.; Canas, Paula M.; Tome, Angelo R. ; Palmeira, Carlos M. ; Lopes, Joao Pedro; Cunha, Rodrigo A.; Agostinho, Paula; Ferreira, Samira G.;
PUBLISHED: 2023, SOURCE: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, VOLUME: 24, ISSUE: 8

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TITLE: Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors Full Text
AUTHORS: Nikolaou, Panagiota Efstathia; Lambrinidis, George; Georgiou, Maria; Karagiannis, Dimitrios; Efentakis, Panagiotis; Bessis Lazarou, Pavlos; Founta, Konstantina; Kampoukos, Stavros; Konstantin, Vasilis; Palmeira, Carlos M. ; Davidson, Sean M.; Lougiakis, Nikolaos; Marakos, Panagiotis; Pouli, Nicole; Mikros, Emmanuel; Andreadou, Ioanna;
PUBLISHED: 2023, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 66, ISSUE: 22

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TITLE: Loss of epigenetic information as a cause of mammalian aging
AUTHORS: Yang, Jae Hyun; Hayano, Motoshi; Griffin, Patrick T.; Amorim, Joao A.; Bonkowski, Michael S.; Apostolides, John K.; Salfati, Elias L.; Blanchette, Marco; Munding, Elizabeth M.; Bhakta, Mital; Chew, Yap Ching; Guo, Wei; Yang, Xiaojing; Maybury Lewis, Sun; Tian, Xiao; Ross, Jaime M.; Coppotelli, Giuseppe; Meer, Margarita V.; Rogers Hammond, Ryan; Vera, Daniel L.; Lu, Yuancheng Ryan; Pippin, Jeffrey W.; Creswell, Michael L.; Dou, Zhixun; Xu, Caiyue; Mitchell, Sarah J.; Das, Abhirup; O'Connell, Brendan L.; Thakur, Sachin; Kane, Alice E.; Su, Qiao; Mohri, Yasuaki; Nishimura, Emi K.; Schaevitz, Laura; Garg, Neha; Balta, Ana Maria; Rego, Meghan A.; Gregory Ksander, Meredith; Jakobs, Tatjana C.; Zhong, Lei; Wakimoto, Hiroko; Andari, Jihad El; Grimm, Dirk; Mostoslavsky, Raul; Wagers, Amy J.; Tsubota, Kazuo; Bonasera, Stephen J.; Palmeira, Carlos M. ; Seidman, Jonathan G.; Seidman, Christine E.; Wolf, Norman S.; Kreiling, Jill A.; Sedivy, John M.; Murphy, George F.; Green, Richard E.; Garcia, Benjamin A.; Berger, Shelley L.; Oberdoerffer, Philipp; Shankland, Stuart J.; Gladyshev, Vadim N.; Ksander, Bruce R.; Pfenning, Andreas R.; Rajman, Luis A.; Sinclair, David A.; ...More
PUBLISHED: 2023, SOURCE: CELL, VOLUME: 186, ISSUE: 2

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