Patricia Isabel Gomes Alves
AuthID: R-000-E1B
1
TITLE: Enhancing gene therapy vectors manufacturing: CEBPA as a master regulator of rAAV biogenesis Full Text
AUTHORS: Moura, Filipa; Antunes, Mariana; Correia, Ricardo; Roldao, Antonio; Gomes Alves, Patricia; Alves, Paula Marques; Escandell, Jose M.;
PUBLISHED: 2026, SOURCE: JOURNAL OF BIOLOGICAL ENGINEERING, VOLUME: 20, ISSUE: 1
AUTHORS: Moura, Filipa; Antunes, Mariana; Correia, Ricardo; Roldao, Antonio; Gomes Alves, Patricia; Alves, Paula Marques; Escandell, Jose M.;
PUBLISHED: 2026, SOURCE: JOURNAL OF BIOLOGICAL ENGINEERING, VOLUME: 20, ISSUE: 1
2
TITLE: Streamlined rAAV HeLaS3 producer cell line generation via GS selection Full Text
AUTHORS: Antunes, Mariana; Moura, Filipa; Sebastian, Ivy Rose; Alves, Paula; Gomes Alves, Patricia; Escandell, Jose M.;
PUBLISHED: 2026, SOURCE: SCIENTIFIC REPORTS, VOLUME: 16, ISSUE: 1
AUTHORS: Antunes, Mariana; Moura, Filipa; Sebastian, Ivy Rose; Alves, Paula; Gomes Alves, Patricia; Escandell, Jose M.;
PUBLISHED: 2026, SOURCE: SCIENTIFIC REPORTS, VOLUME: 16, ISSUE: 1
3
TITLE: Multispecific antibodies: Bioanalytics for early-stage screening and characterization of mispairing profiles Full Text
AUTHORS: Melo, Catarina; Carvalho, Sofia B.; Sebastiao, Maria J.; Gomes, Ricardo A.; Sousa, Pedro M. F.; Gomes Alves, Patricia;
PUBLISHED: 2025, SOURCE: PLOS ONE, VOLUME: 20, ISSUE: 11
AUTHORS: Melo, Catarina; Carvalho, Sofia B.; Sebastiao, Maria J.; Gomes, Ricardo A.; Sousa, Pedro M. F.; Gomes Alves, Patricia;
PUBLISHED: 2025, SOURCE: PLOS ONE, VOLUME: 20, ISSUE: 11
4
TITLE: SWATH-MS as a strategy for CHO host cell protein identification and quantification supporting the characterization of mAb purification platforms Full Text
AUTHORS: Carvalho, Sofia B.; Profit, Ludivine; Krishnan, Sushmitha; Gomes, Ricardo A.; Alexandre, Bruno M.; Clavier, Severine; Hoffman, Michael; Brower, Kevin; Gomes Alves, Patricia;
PUBLISHED: 2024, SOURCE: JOURNAL OF BIOTECHNOLOGY, VOLUME: 384
AUTHORS: Carvalho, Sofia B.; Profit, Ludivine; Krishnan, Sushmitha; Gomes, Ricardo A.; Alexandre, Bruno M.; Clavier, Severine; Hoffman, Michael; Brower, Kevin; Gomes Alves, Patricia;
PUBLISHED: 2024, SOURCE: JOURNAL OF BIOTECHNOLOGY, VOLUME: 384
5
TITLE: Miniaturization of hiPSC-derived 3D neural cultures in stirred-tank bioreactors for parallelized preclinical assessment of rAAV
AUTHORS: Gomes, Catarina M.; Sebastiao, Maria Joao; Silva, Gabriela; Moura, Filipa; Simao, Daniel; Gomes Alves, Patricia; Alves, Paula M.; Brito, Catarina;
PUBLISHED: 2024, SOURCE: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, VOLUME: 12
AUTHORS: Gomes, Catarina M.; Sebastiao, Maria Joao; Silva, Gabriela; Moura, Filipa; Simao, Daniel; Gomes Alves, Patricia; Alves, Paula M.; Brito, Catarina;
PUBLISHED: 2024, SOURCE: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, VOLUME: 12
6
TITLE: TUNING CAR-T CELL PHENOTYPE THROUGH ENHANCED BIOPROCESS CONTROL IN AN AUTOMATED STIRRED-TANK BIOREACTOR
AUTHORS: Tomas, H.; Costa, M. S.; Costa, C.; Duarte, N.; Alves, P.; Costa, M.; Serra, M.;
PUBLISHED: 2024, SOURCE: CYTOTHERAPY, VOLUME: 26, ISSUE: 6
AUTHORS: Tomas, H.; Costa, M. S.; Costa, C.; Duarte, N.; Alves, P.; Costa, M.; Serra, M.;
PUBLISHED: 2024, SOURCE: CYTOTHERAPY, VOLUME: 26, ISSUE: 6
INDEXED IN: 
WOS
WOS7
TITLE: OPTIMIZING T CELL EXPANSION IN STIRRED-TANK BIOREACTORS TOWARDS SCALABLE MANUFACTURING OF LESS EXHAUSTED CELL PHENOTYPES
AUTHORS: Costa, M. S.; Costa, C.; Duarte, N.; Alves, P.; Costa, M.; Serra, M.;
PUBLISHED: 2024, SOURCE: CYTOTHERAPY, VOLUME: 26, ISSUE: 6
AUTHORS: Costa, M. S.; Costa, C.; Duarte, N.; Alves, P.; Costa, M.; Serra, M.;
PUBLISHED: 2024, SOURCE: CYTOTHERAPY, VOLUME: 26, ISSUE: 6
INDEXED IN: WOS
WOS8
TITLE: Towards a scalable bioprocess for rAAV production using a HeLa stable cell line Full Text
AUTHORS: Escandell, Jose; Moura, Filipa; Carvalho, Sofia B.; Silva, Ricardo J. S.; Correia, Ricardo; Roldao, Antonio; Gomes Alves, Patricia; Alves, Paula M.;
PUBLISHED: 2023, SOURCE: BIOTECHNOLOGY AND BIOENGINEERING, VOLUME: 120, ISSUE: 9
AUTHORS: Escandell, Jose; Moura, Filipa; Carvalho, Sofia B.; Silva, Ricardo J. S.; Correia, Ricardo; Roldao, Antonio; Gomes Alves, Patricia; Alves, Paula M.;
PUBLISHED: 2023, SOURCE: BIOTECHNOLOGY AND BIOENGINEERING, VOLUME: 120, ISSUE: 9
9
TITLE: Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody
AUTHORS: Maria João Sebastião; Michael Hoffman; José Escandell; Fatemeh Tousi; Jin Zhang; Bruno Figueroa; Christine DeMaria; Patrícia Gomes Alves;
PUBLISHED: 2023, SOURCE: Biomedicines, VOLUME: 11, ISSUE: 11
AUTHORS: Maria João Sebastião; Michael Hoffman; José Escandell; Fatemeh Tousi; Jin Zhang; Bruno Figueroa; Christine DeMaria; Patrícia Gomes Alves;
PUBLISHED: 2023, SOURCE: Biomedicines, VOLUME: 11, ISSUE: 11
10
TITLE: Leveraging rAAV bioprocess understanding and next generation bioanalytics development
AUTHORS: Escandell, Jose M.; Pais, Daniel Am; Carvalho, Sofia B.; Vincent, Karen; Gomes Alves, Patricia; Alves, Paula M.;
PUBLISHED: 2022, SOURCE: CURRENT OPINION IN BIOTECHNOLOGY, VOLUME: 74
AUTHORS: Escandell, Jose M.; Pais, Daniel Am; Carvalho, Sofia B.; Vincent, Karen; Gomes Alves, Patricia; Alves, Paula M.;
PUBLISHED: 2022, SOURCE: CURRENT OPINION IN BIOTECHNOLOGY, VOLUME: 74
