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TITLE: Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance
AUTHORS: Tye, Mark A.; Payne, N. Connor; Johansson, Catrine; Singh, Kritika; Santos, Sofia A.; Fagbami, Lola; Pant, Akansha; Sylvester, Kayla; Luth, Madeline R.; Marques, Sofia; Whitman, Malcolm; Mota, Maria M.; Winzeler, Elizabeth A.; Lukens, Amanda K.; Derbyshire, Emily R.; Oppermann, Udo; Wirth, Dyann F.; Mazitschek, Ralph;
PUBLISHED: 2022, SOURCE: NATURE COMMUNICATIONS, VOLUME: 13, ISSUE: 1
INDEXED IN: Scopus WOS
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TITLE: The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs
AUTHORS: Jonathan D Herman; Lauren R Pepper; Joseph F Cortese; Guillermina Estiu; Kevin Galinsky; Vanessa Zuzarte Luis; Emily R Derbyshire; Ulf Ribacke; Amanda K Lukens; Sofia A Santos; Vishal Patel; Clary B Clish; William J Sullivan; Huihao H Zhou; Selina E Bopp; Paul Schimmel; Susan Lindquist; Jon Clardy; Maria M Mota; Tracy L Keller; Malcolm Whitman; Olaf Wiest; Dyann F Wirth; Ralph Mazitschek; ...More
PUBLISHED: 2015, SOURCE: SCIENCE TRANSLATIONAL MEDICINE, VOLUME: 7, ISSUE: 288
INDEXED IN: Scopus WOS CrossRef
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TITLE: Chemical Interrogation of the Malaria Kinome  Full Text
AUTHORS: Emily R Derbyshire; Vanessa Zuzarte Luis; Andreia D Magalhaes; Nobutaka Kato; Paul C Sanschagrin; Jinhua H Wang; Wenjun J Zhou; Chandrasekhar V Miduturu; Ralph Mazitschek; Piotr Sliz; Maria M Mota; Nathanael S Gray; Jon Clardy;
PUBLISHED: 2014, SOURCE: CHEMBIOCHEM, VOLUME: 15, ISSUE: 13
INDEXED IN: Scopus WOS CrossRef
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TITLE: Liver-stage malaria parasites vulnerable to diverse chemical scaffolds
AUTHORS: Emily R Derbyshire; Miguel Prudencio ; Maria M Mota ; Jon Clardy;
PUBLISHED: 2012, SOURCE: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, VOLUME: 109, ISSUE: 22
INDEXED IN: Scopus WOS CrossRef
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TITLE: The Next Opportunity in Anti-Malaria Drug Discovery: The Liver Stage  Full Text
AUTHORS: Emily R Derbyshire; Maria M Mota ; Jon Clardy;
PUBLISHED: 2011, SOURCE: PLOS PATHOGENS, VOLUME: 7, ISSUE: 9
INDEXED IN: Scopus WOS CrossRef
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TITLE: Use of a Selective Inhibitor To Define the Chemotherapeutic Potential of the Plasmodial Hexose Transporter in Different Stages of the Parasite's Life Cycle
AUTHORS: Ksenija Slavic ; Michael J Delves; Miguel Prudencio ; Arthur M Talman; Ursula Straschil; Elvira T Derbyshire; Zhengyao Y Xu; Robert E Sinden; Maria M Mota ; Christophe Morin; Rita Tewari; Sanjeev Krishna; Henry M Staines;
PUBLISHED: 2011, SOURCE: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, VOLUME: 55, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef
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TITLE: Plasmodial sugar transporters as anti-malarial drug targets and comparisons with other protozoa  Full Text
AUTHORS: Slavic, K; Krishna, S; Derbyshire, ET; Staines, HM;
PUBLISHED: 2011, SOURCE: Malaria Journal, VOLUME: 10, ISSUE: 1
INDEXED IN: Scopus CrossRef
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TITLE: Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells  Full Text
AUTHORS: Miguel Prudencio ; Elvira T Derbyshire; Catarina A Marques; Sanjeev Krishna; Maria M Mota ; Henry M Staines;
PUBLISHED: 2009, SOURCE: CELLULAR MICROBIOLOGY, VOLUME: 11, ISSUE: 10
INDEXED IN: Scopus WOS CrossRef