Jim Iley
AuthID: R-001-HPP
1
TITLE: N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases Full Text
AUTHORS: Ana Bela Santana; Susana D Lucas ; Lidia M Goncalves; Henrique F Correia; Teresa A F Cardote; Rita C Guedes ; Jim Iley; Rui Moreira ;
PUBLISHED: 2012, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 22, ISSUE: 12
AUTHORS: Ana Bela Santana; Susana D Lucas ; Lidia M Goncalves; Henrique F Correia; Teresa A F Cardote; Rita C Guedes ; Jim Iley; Rui Moreira ;
PUBLISHED: 2012, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 22, ISSUE: 12
2
TITLE: A carbamate-based approach to primaquine prodrugs: Antimalarial activity, chemical stability and enzymatic activation Full Text
AUTHORS: Graca Mata; Virgilio E do Rosario; Jim Iley; Luis Constantino ; Rui Moreira ;
PUBLISHED: 2012, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY, VOLUME: 20, ISSUE: 2
AUTHORS: Graca Mata; Virgilio E do Rosario; Jim Iley; Luis Constantino ; Rui Moreira ;
PUBLISHED: 2012, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY, VOLUME: 20, ISSUE: 2
3
TITLE: Basic hydrolysis of quinolinyl N,N-dimethylcarbamates: a two-step mechanism Full Text
AUTHORS: Daniel Silva ; Fatima Norberto; Susana Santos ; Jim Iley;
PUBLISHED: 2011, SOURCE: JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, VOLUME: 24, ISSUE: 11
AUTHORS: Daniel Silva ; Fatima Norberto; Susana Santos ; Jim Iley;
PUBLISHED: 2011, SOURCE: JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, VOLUME: 24, ISSUE: 11
4
TITLE: Synthesis, stability, biochemical and pharmacokinetic properties of a new potent and selective 4-oxo-beta beta-lactam inhibitor of human leukocyte elastase Full Text
AUTHORS: Jalmira Mulchande; Sandra I Simoes ; Maria M Gaspar ; Carla V Eleuterio; Rudi Oliveira; Maria E M Cruz ; Rui Moreira ; Jim Iley;
PUBLISHED: 2011, SOURCE: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, VOLUME: 26, ISSUE: 2
AUTHORS: Jalmira Mulchande; Sandra I Simoes ; Maria M Gaspar ; Carla V Eleuterio; Rudi Oliveira; Maria E M Cruz ; Rui Moreira ; Jim Iley;
PUBLISHED: 2011, SOURCE: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, VOLUME: 26, ISSUE: 2
5
TITLE: 4-Oxo-beta-lactams (Azetidine-2,4-diones) Are Potent and Selective Inhibitors of Human Leukocyte Elastase Full Text
AUTHORS: Jalmira Mulchande; Rudi Oliveira; Marta Carrasco; Luis Gouveia ; Rita C Guedes ; Jim Iley; Rui Moreira ;
PUBLISHED: 2010, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 53, ISSUE: 1
AUTHORS: Jalmira Mulchande; Rudi Oliveira; Marta Carrasco; Luis Gouveia ; Rita C Guedes ; Jim Iley; Rui Moreira ;
PUBLISHED: 2010, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 53, ISSUE: 1
6
TITLE: Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho[2,3-d]isoxazole-4,9-diones Full Text
AUTHORS: Maria M M Santos ; Natalia Faria; Jim Iley; Simon J Coles; Michael B Hursthouse; Luz L Martins ; Rui Moreira ;
PUBLISHED: 2010, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 20, ISSUE: 1
AUTHORS: Maria M M Santos ; Natalia Faria; Jim Iley; Simon J Coles; Michael B Hursthouse; Luz L Martins ; Rui Moreira ;
PUBLISHED: 2010, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 20, ISSUE: 1
7
TITLE: Dopamine- and tyramine-based derivatives of triazenes: Activation by tyrosinase and implications for prodrug design Full Text
AUTHORS: Jesus J Perry; Eduarda Mendes; Ana Luisa Simplicio ; Ana Coelho ; Ricardo V Soares; Jim Iley; Rui Moreira ; Ana Paula Francisco;
PUBLISHED: 2009, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 44, ISSUE: 8
AUTHORS: Jesus J Perry; Eduarda Mendes; Ana Luisa Simplicio ; Ana Coelho ; Ricardo V Soares; Jim Iley; Rui Moreira ; Ana Paula Francisco;
PUBLISHED: 2009, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 44, ISSUE: 8
8
TITLE: Towards an efficient prodrug of the alkylating metabolite monomethyltriazene: Synthesis and stability of N-acylamino acid derivatives of triazenes Full Text
AUTHORS: Maria de Jesus Perry; Emilia Carvalho; Eduarda Rosa; Jim Iley;
PUBLISHED: 2009, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 44, ISSUE: 3
AUTHORS: Maria de Jesus Perry; Emilia Carvalho; Eduarda Rosa; Jim Iley;
PUBLISHED: 2009, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 44, ISSUE: 3
9
TITLE: Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design Full Text
AUTHORS: Tiago Rodrigues; Rui Moreira ; Rita C Guedes ; Jim Iley; Francisca Lopes ;
PUBLISHED: 2008, SOURCE: ARCHIV DER PHARMAZIE, VOLUME: 341, ISSUE: 6
AUTHORS: Tiago Rodrigues; Rui Moreira ; Rita C Guedes ; Jim Iley; Francisca Lopes ;
PUBLISHED: 2008, SOURCE: ARCHIV DER PHARMAZIE, VOLUME: 341, ISSUE: 6
10
TITLE: Azetidine-2,4-diones (4-oxo-beta-lactams) as scaffolds for designing elastase inhibitors Full Text
AUTHORS: Jalmira Mulchande; Rita C Guedes ; Wing Yin Tsang; Michael I Page; Rui Moreira ; Jim Iley;
PUBLISHED: 2008, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 51, ISSUE: 6
AUTHORS: Jalmira Mulchande; Rita C Guedes ; Wing Yin Tsang; Michael I Page; Rui Moreira ; Jim Iley;
PUBLISHED: 2008, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 51, ISSUE: 6
