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TITLE: N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases  Full Text
AUTHORS: Ana Bela Santana; Susana D Lucas ; Lidia M Goncalves; Henrique F Correia; Teresa A F Cardote; Rita C Guedes ; Jim Iley; Rui Moreira ;
PUBLISHED: 2012, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 22, ISSUE: 12
INDEXED IN: Scopus WOS CrossRef
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TITLE: Design, synthesis, and enzymatic evaluation of N-1-acyloxyalkyl- and N-1-oxazolidin-2,4-dion-5-yl-substituted beta-lactams as novel inhibitors of human leukocyte elastase  Full Text
AUTHORS: Moreira, R ; Santana, AB; Iley, J; Neres, J; Douglas, KT; Horton, PN; Hursthouse, MB;
PUBLISHED: 2005, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 48, ISSUE: 15
INDEXED IN: Scopus WOS CrossRef
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TITLE: Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors  Full Text
AUTHORS: Clemente, A; Domingos, A; Grancho, AP; Iley, J; Moreira, R ; Neres, J; Palma, N; Santana, AB; Valente, E;
PUBLISHED: 2001, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 11, ISSUE: 8
INDEXED IN: Scopus WOS CrossRef