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TITLE: Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5  Full Text
AUTHORS: Suenkel, Benjamin; Valente, Sergio; Zwergel, Clemens; Weiss, Sandra; Di Bello, Elisabetta; Fioravanti, Rossella; Aventaggiato, Michele; Amorim, Joao A.; Garg, Neha; Kumar, Surinder; Lombard, David B.; Hu, Tuo; Singh, Pankaj K.; Tafani, Marco; Palmeira, Carlos M.; Sinclair, David; Mai, Antonello; Steegborn, Clemens;
PUBLISHED: 2022, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 65, ISSUE: 20
INDEXED IN: Scopus WOS
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TITLE: The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function  Full Text
AUTHORS: Joao S Teodoro; Joao A Amorim; Ivo F Machado; Ana C Castela; Clemens Steegborn; David A Sinclair; Anabela P Rolo; Carlos M Palmeira;
PUBLISHED: 2020, SOURCE: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, VOLUME: 21, ISSUE: 14
INDEXED IN: Scopus WOS
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TITLE: The interplay between cAMP and Sirtuins as a nexus of mitochondrial and metabolic control  Full Text
AUTHORS: Amorim, J; Teodoro, J; Silva, R; Rolo, A; Steegborn, C; Sinclair, D; Palmeira, C;
PUBLISHED: 2018, SOURCE: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, VOLUME: 48
INDEXED IN: WOS
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TITLE: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease  Full Text
AUTHORS: Rita Machado de Oliveira; Hugo Vicente Miranda ; Laetitia Francelle; Raquel Pinho; Eva M Szegoe; Renato Martinho; Francesca Munari; Diana F Lazaro; Sebastien Moniot; Patricia Guerreiro; Luis Fonseca; Zrinka Marijanovic; Pedro Antas; Ellen Gerhardt; Francisco Javier Enguita; Bruno Fauvet; Deborah Penque; Teresa Faria Pais; Qiang Tong; Stefan Becker; Sebastian Kuegler; Hilal Ahmed Lashuel; Clemens Steegborn; Markus Zweckstetter; Tiago Fleming Outeiro; ...More
PUBLISHED: 2017, SOURCE: PLOS BIOLOGY, VOLUME: 15, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef: 107
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TITLE: SIRT2-and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models
AUTHORS: Luisa Quinti; Malcolm Casale; Sebastien Moniot; Teresa F Pais; Michael J Van Kanegan; Linda S Kaltenbach; Judit Pallos; Ryan G Lim; Sharadha Dayalan Naidu; Heike Runne; Lisa Meisel; Nazifa Abdul Rauf; Dmitriy Leyfer; Michele M Maxwell; Eddine Saiah; John E Landers; Ruth Luthi Carter; Ruben Abagyan; Albena T Dinkova Kostova; Clemens Steegborn; Lawrence L Marsh; Donald C Lo; Leslie M Thompson; Aleksey G Kazantsev; ...More
PUBLISHED: 2016, SOURCE: CELL CHEMICAL BIOLOGY, VOLUME: 23, ISSUE: 7
INDEXED IN: Scopus WOS CrossRef