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TITLE: Combinatorial CRISPR screen identifies fitness effects of gene paralogues
AUTHORS: Thompson, NA; Ranzani, M; van der Weyden, L; Iyer, V; Offord, V; Droop, A; Behan, F; Gonçalves, Emanuel ; Speak, A; Iorio, F; Hewinson, J; Harle, V; Robertson, H; Anderson, E; Fu, B; Yang, F; Zagnoli Vieira, G; Chapman, P; Del Castillo Velasco Herrera, M; Garnett, MJ; Jackson, SP; Adams, DJ; ...More
PUBLISHED: 2021, SOURCE: Nature Communications, VOLUME: 12, ISSUE: 1
INDEXED IN: Scopus CrossRef
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TITLE: Integrated cross-study datasets of genetic dependencies in cancer
AUTHORS: Pacini, C; Dempster, JM; Boyle, I; Gonçalves, Emanuel ; Najgebauer, H; Karakoc, E; van der Meer, D; Barthorpe, A; Lightfoot, H; Jaaks, P; McFarland, JM; Garnett, MJ; Tsherniak, A; Iorio, F;
PUBLISHED: 2021, SOURCE: Nature Communications, VOLUME: 12, ISSUE: 1
INDEXED IN: Scopus CrossRef
3
TITLE: Minimal genome-wide human CRISPR-Cas9 library
AUTHORS: Gonçalves, Emanuel ; Thomas, M; Behan, FM; Picco, G; Pacini, C; Allen, F; Vinceti, A; Sharma, M; Jackson, DA; Price, S; Beaver, CM; Dovey, O; Parry Smith, D; Iorio, F; Parts, L; Yusa, K; Garnett, MJ;
PUBLISHED: 2021, SOURCE: GENOME BIOLOGY, VOLUME: 22, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 1
4
TITLE: Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets  Full Text
AUTHORS: Dwane, L; Behan, FM; Gonçalves, Emanuel ; Lightfoot, H; Yang, WJ; van der Meer, D; Shepherd, R; Pignatelli, M; Iorio, F; Garnett, MJ;
PUBLISHED: 2021, SOURCE: NUCLEIC ACIDS RESEARCH, VOLUME: 49, ISSUE: D1
INDEXED IN: Scopus WOS CrossRef: 1
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TITLE: Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens
AUTHORS: Gonçalves, Emanuel ; Segura Cabrera, A; Pacini, C; Picco, G; Behan, FM; Jaaks, P; Coker, EA; van der Meer, D; Barthorpe, A; Lightfoot, H; Mironenko, T; Beck, A; Richardson, L; Yang, W; Lleshi, E; Hall, J; Tolley, C; Hall, C; Mali, I; Thomas, F; Morris, J; Leach, AR; Lynch, JT; Sidders, B; Crafter, C; Iorio, F; Fawell, S; Garnett, MJ; ...More
PUBLISHED: 2020, SOURCE: Molecular Systems Biology, VOLUME: 16, ISSUE: 7
INDEXED IN: Scopus CrossRef: 6
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TITLE: Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway
AUTHORS: Chai, AWY; Yee, PS; Price, S; Yee, SM; Lee, HM; Tiong, VKH; Gonçalves, Emanuel ; Behan, FM; Bateson, J; Gilbert, J; Tan, AC; McDermott, U; Garnett, MJ; Cheong, SC;
PUBLISHED: 2020, SOURCE: ELIFE, VOLUME: 9
INDEXED IN: Scopus WOS CrossRef
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TITLE: SBML Level 3: an extensible format for the exchange and reuse of biological models
AUTHORS: Keating, SM; Waltemath, D; König, M; Zhang, F; Dräger, A; Chaouiya, C; Bergmann, FT; Finney, A; Gillespie, CS; Helikar, T; Hoops, S; Malik Sheriff, RS; Moodie, SL; Moraru, II; Myers, CJ; Naldi, A; Olivier, BG; Sahle, S; Schaff, JC; Smith, LP; Swat, MJ; Thieffry, D; Watanabe, L; Wilkinson, DJ; Blinov, ML; Begley, K; Faeder, JR; Gómez, HF; Hamm, TM; Inagaki, Y; Liebermeister, W; Lister, AL; Lucio, D; Mjolsness, E; Proctor, CJ; Raman, K; Rodriguez, N; Shaffer, CA; Shapiro, BE; Stelling, J; Swainston, N; Tanimura, N; Wagner, J; Meier Schellersheim, M; Sauro, HM; Palsson, B; Bolouri, H; Kitano, H; Funahashi, A; Hermjakob, H; Doyle, JC; Hucka, M; Adams, RR; Allen, NA; Angermann, BR; Antoniotti, M; Bader, GD; Červený, J; Courtot, M; Cox, CD; Dalle Pezze, P; Demir, E; Denney, WS; Dharuri, H; Dorier, J; Drasdo, D; Ebrahim, A; Eichner, J; Elf, J; Endler, L; Evelo, CT; Flamm, C; Fleming, RMT; Fröhlich, M; Glont, M; Gonçalves, Emanuel ; Golebiewski, M; Grabski, H; Gutteridge, A; Hachmeister, D; Harris, LA; Heavner, BD; Henkel, R; Hlavacek, WS; Hu, B; Hyduke, DR; de Jong, H; Juty, N; Karp, PD; Karr, JR; Kell, DB; Keller, R; Kiselev, I; Klamt, S; Klipp, E; Knüpfer, C; Kolpakov, F; Krause, F; Kutmon, M; Laibe, C; Lawless, C; Li, L; Loew, LM; Machne, R; Matsuoka, Y; Mendes, P; Mi, H; Mittag, F; Monteiro, PT; Natarajan, KN; Nielsen, PMF; Nguyen, T; Palmisano, A; Pettit, JB; Pfau, T; Phair, RD; Radivoyevitch, T; Rohwer, JM; Ruebenacker, OA; Saez Rodriguez, J; Scharm, M; Schmidt, H; Schreiber, F; Schubert, M; Schulte, R; Sealfon, SC; Smallbone, K; Soliman, S; Stefan, MI; Sullivan, DP; Takahashi, K; Teusink, B; Tolnay, D; Vazirabad, I; von Kamp, A; Wittig, U; Wrzodek, C; Wrzodek, F; Xenarios, I; Zhukova, A; Zucker, J; ...More
PUBLISHED: 2020, SOURCE: MOLECULAR SYSTEMS BIOLOGY, VOLUME: 16, ISSUE: 8
INDEXED IN: Scopus WOS CrossRef: 10
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TITLE: Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
AUTHORS: Dempster, JM; Pacini, C; Pantel, S; Behan, FM; Green, T; Krill Burger, J; Beaver, CM; Younger, ST; Zhivich, V; Najgebauer, H; Allen, F; Gonçalves, Emanuel ; Shepherd, R; Doench, JG; Yusa, K; Vazquez, F; Parts, L; Boehm, JS; Golub, TR; Hahn, WC; Root, DE; Garnett, MJ; Tsherniak, A; Iorio, F; ...More
PUBLISHED: 2019, SOURCE: NATURE COMMUNICATIONS, VOLUME: 10, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 41
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TITLE: Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening
AUTHORS: Picco, G; Chen, ED; Alonso, LG; Behan, FM; Gonçalves, Emanuel ; Bignell, G; Matchan, A; Fu, BY; Banerjee, R; Andersonl, E; Butler, A; Benes, CH; McDermott, U; Dow, D; Iorio, F; Stronach, E; Yang, FT; Yusa, K; Saez Rodriguez, J; Garnett, MJ;
PUBLISHED: 2019, SOURCE: NATURE COMMUNICATIONS, VOLUME: 10, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 30
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TITLE: Multi-omics Characterization of Interactionmediated Control of Human Protein Abundance levels
AUTHORS: Sousa, A; Gonçalves, Emanuel ; Mirauta, B; Ochoa, D; Stegle, O; Beltrao, P;
PUBLISHED: 2019, SOURCE: MOLECULAR & CELLULAR PROTEOMICS, VOLUME: 18, ISSUE: 8
INDEXED IN: Scopus WOS CrossRef: 4
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